Comparative detoxication. 6. The metabolism of 6-amino-4 nitro-o-cresol and 4:6-dinitro-o-cresol in locusts*

Some observations on the absorption and excretion of 4:6-dinitro-o-cresol. II. The elimination of 4:6-dinitro-o-cresol by man and by animals.

Harvey, Bidstrup & Bonnell (I951) have shown thaV 4:6-dinitro-o-cresol (DNOC) accumulates in man as the result of small daily doses and have shown that DNOC is very slowly eliminated from the body. This observation has received support from the evidence of a clinical case of a seriously poisoned spray operator reported by Pollard & Filbee (1951). A preliminary account of the work reported in th...

[An unusual suicide with dinitro-o-cresol].

Reproductive toxicology. o-Cresol.

Background: Data from Egyptian studies provide widely varying estimates on the prevalence of premalignant and malignant cervical abnormalities and human papilloma virus (HPVs) infection. To define the prevalence and risk factors of pre-invasive and invasive cervical cancer (cacx), a community based full-scale cross sectional, household survey including 5453 women aged between 35 and 60 years wa...

The effect of dinitro-o-cresol on the deposition of liver glycogen in the rat.

J. C. LAIDLAW AND L. YOUNG I953 Folin, 0. (1905). J. biol. Chem. 1, 131. Hele, T. S. (1924). Biochem. J. 18, 110. Hele, T. S. (1931). Biochem. J. 25, 1736. Laidlaw, J. C. (1947). Thesis, University of Toronto. Laidlaw, J. C. & Young, L. (1948). Biochem. J. 42, Proc. 1. Lawrie, N. R. (1931). Biochem. J. 25, 1037. Manson, L. A. & Young, L. (1950). Biochem. J. 47, 170. Rhode, H. (1923). Hoppe-Seyl...

Mechanism of Action of the Herbicide 4,6-Dinitro-o-cresol in Photosynthesis

The herbicide 4,6-dinitro-o-cresol inhibits electron transport to ferricyanide and non-cyclic photophosphorylation for 50% at about 15 /am. At higher concentrations the photosystem I depen­ dent M ehler reaction ascorbate/dichlorophenolindophenol to methyl viologen is stimulated, while cyclic photophosphorylation is inhibited. The herbicide thus is an inhibitory uncoupler. Although the chemical...